Everything about Hemorrhagic Cystitis totally explained
Hemorrhagic cystitis or
Haemorrhagic cystitis is diffuse inflammation of the bladder leading to
hemorrhage. This is seen most often in cancer patients as a complication of therapy. It occurs in women. Pus is present in the urine but no organism can be cultured in the urine
Causes of hemorrhagic cystitis include chemotherapy (for example
cyclophosphamide), radiation, or viral infection (for example with the [[BKvirus] or Adenovirus] in
bone marrow transplant patients. In the case of hemorrhagic cystitis from cyclophosphamide, this can be prevented through aggressive hydration and the use of
mesna, which neutralizes the toxicity of
acrolein, a metabolite of cyclophosphamide.
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